With an estimated 5.2 million people
infected with Hepatitis C Virus (HCV) you probably know someone that is infected. A lot
of famous people have come out and stated that they are infected with HCV. One
of the more famous people that claimed to be infected with HCV is Keith Richards.
Keith Richards is most famously known for being the founding member of The
Rolling Stones. Keith Richards in relation to Hepatitis C Virus is noted for
his statement that he was cured of HCV by "just being me." So you
probably don't believe him but what if I told you that it very well could be
true. In fact 14 to 40% of those exposed to HCV spontaneously clear the virus.
Some of the major factors associated with spontaneous clearance include a
single exposure, younger age at infection, female sex, and certain HLA genes.
Additionally African Americans and Asian Americans appear to be less likely
than Hispanic or white Americans to clear the virus spontaneously. Of those who
do not clear the virus and progress into chronic Hepatitis C Virus there are
some treatment options. The treatment itself is one of the main problems
associated with Hepatitis C virus. The current treatment for chronic Hepatitis
C virus is pegylated interferon along with ribivarin. The results of this
expensive treatment only cure patients approximately 50% of the time and have toxic
side effects associated with it. Multiple factors have been found to be
associated with response to this treatment including viral and host factors.
The viral factor that has been found to be the best predictor of response to
treatment is virus genotype, with genotype 2 and 3 reaching 70% to 80%
sustained response. Several commercial assays for HCV genotyping are available
for use in clinical laboratories.
I had no idea about the type of treatment for Chronic Hepatitis C. Current standard-of-care treatment for chronic hepatitis C virus (HCV) infection consists for either 24 weeks (for people with HCV genotypes 2 or 3) or 48 weeks (for hard-to-treat genotypes 1 or 4). "Extending the treatment duration from 48 to 72 weeks in genotype 1 infected patients with late virological response improves response," study authors say." The treatment for Chronic Hepatitis C has symptoms that are extremely difficult to cope with. Treatment of chronic hepatitis C can make you weak, fatigued, have a poor appetite, muscle and body aches, diarrhea, nausea, hair loss, shortness of breath. Pegylated interferon is the best treatment thus far, but can me critical upon the patient.
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